Mu-Jie Lu

Credit: Vivian Abagiu

“I want to understand on a molecular level the real basic original mechanics and how genes drive a phenotype or a disease.”

Doctoral candidate in cell and molecular biology in the lab of Professor Lulu Cambronne. Interviewed by Esther Robards-Forbes.

What drew you to study life sciences?

I chose biology because we know so much about the nature of science, though we don’t really understand how everything works, even in our own bodies. When we go deeper, into organs and cells, there are more questions. How does a stem cell know what type of cell to become? How do they work together to make a whole body? I want to understand on a molecular level the real basic original mechanics and how genes drive a phenotype or a disease, because if we can understand what is happening at a basic level, treatments and cures are possible. I really want my research to have some applications and to help people live longer, healthier lives.  

Why did you want to study metabolic diseases specifically?

Because everybody needs glucose and fatty acid to provide the energy cells need to survive, but recently we discovered that they’re not just a source of energy; they also change the cell behavior. Understanding how cells coordinate nutrient utilization, gene expression and cellular behaviors is important. When these go wrong, it can lead to diseases. Our lab’s insights could lead to new treatments.

I hear you like to hike. What’s been your favorite hike? And where do you want to go next?

Enchanted Rock is my favorite. I’ve never hiked to the top of a giant dome before, and it gave me a gorgeous 360° view from the top. I also like the dome’s reflection on the Moss Lake surface. Next, I want to go to Big Bend. 

What has your experience as an international student been like at UT?

Because I come from a very different cultural background, when I got here, a few things surprised me. There are so many social events here, and people like to socialize a lot. I’m trying to learn how to build connections with other people. This is a good opportunity to make some new friends or meet some new scientists from the other labs. I get nervous sometimes, like many international students. I’m glad that everyone is so friendly and kind. 

What type of career do you want to have?

Good professors and mentors have taught me how to be a good scientist. I would like to have my own lab, do my own research and teach to pass this knowledge and spirit to someone else. Maybe I can motivate my own students to become involved in science and research, and we can help a lot of people.